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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPR All Species: 20.61
Human Site: S32 Identified Species: 34.87
UniProt: P35270 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35270 NP_003115.1 261 28048 S32 P L L A S L L S P G S V L V L
Chimpanzee Pan troglodytes XP_525784 261 27897 S32 P L L A S L L S P G S V L V L
Rhesus Macaque Macaca mulatta XP_001103332 261 28016 S32 P L L A S L L S P G S V L V L
Dog Lupus familis XP_540234 267 28592 A38 R L L A R L L A P G S V L V L
Cat Felis silvestris
Mouse Mus musculus Q64105 261 27865 S33 P Q L A R L L S P G S V M L V
Rat Rattus norvegicus P18297 262 28110 S33 P Q L A G L L S P G S V L L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520473 236 25629 E26 G M E G A C A E R M E G A Y A
Chicken Gallus gallus Q8JIS3 246 26149 A34 V A L C K A G A R V T A L S R
Frog Xenopus laevis Q7ZY31 263 28687 L36 H E L C P R V L P G S T L L L
Zebra Danio Brachydanio rerio NP_001019601 261 28523 S34 L S V A A R V S P G S V L V L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624245 354 39811 E125 I S F G S I L E K G S H I L L
Nematode Worm Caenorhab. elegans Q21929 251 27201 A34 L S L A K A G A Q V I A F A R
Sea Urchin Strong. purpuratus XP_783056 275 30198 G35 V T L S A K F G P G S V L V L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P40579 254 27462 K27 D V L F S L D K D T V V Y G V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.5 96.9 80.9 N.A. 74.3 74.4 N.A. 46.3 26.4 55.5 52.4 N.A. N.A. 25.4 26 39.6
Protein Similarity: 100 98 99.6 89.1 N.A. 86.5 88.1 N.A. 58.6 44.8 69.9 74.3 N.A. N.A. 41.5 46.3 58.5
P-Site Identity: 100 100 100 80 N.A. 66.6 80 N.A. 0 13.3 40 60 N.A. N.A. 33.3 13.3 53.3
P-Site Similarity: 100 100 100 86.6 N.A. 86.6 86.6 N.A. 13.3 26.6 53.3 80 N.A. N.A. 53.3 20 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 28.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 48.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 58 22 15 8 22 0 0 0 15 8 8 8 % A
% Cys: 0 0 0 15 0 8 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 8 0 8 0 0 0 0 0 0 % D
% Glu: 0 8 8 0 0 0 0 15 0 0 8 0 0 0 0 % E
% Phe: 0 0 8 8 0 0 8 0 0 0 0 0 8 0 0 % F
% Gly: 8 0 0 15 8 0 15 8 0 72 0 8 0 8 0 % G
% His: 8 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % H
% Ile: 8 0 0 0 0 8 0 0 0 0 8 0 8 0 0 % I
% Lys: 0 0 0 0 15 8 0 8 8 0 0 0 0 0 0 % K
% Leu: 15 29 79 0 0 50 50 8 0 0 0 0 65 29 65 % L
% Met: 0 8 0 0 0 0 0 0 0 8 0 0 8 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 36 0 0 0 8 0 0 0 65 0 0 0 0 0 0 % P
% Gln: 0 15 0 0 0 0 0 0 8 0 0 0 0 0 0 % Q
% Arg: 8 0 0 0 15 15 0 0 15 0 0 0 0 0 15 % R
% Ser: 0 22 0 8 36 0 0 43 0 0 72 0 0 8 0 % S
% Thr: 0 8 0 0 0 0 0 0 0 8 8 8 0 0 0 % T
% Val: 15 8 8 0 0 0 15 0 0 15 8 65 0 43 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 8 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _